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50mg/ml - Suspension for injection - Ceftiofur

Ceftiofur is a third generation of Cephalosporin, which is active against many Gram-positive and Gram-negative bacteria, including ß –lactamase producing strains. Ceftiofur inhibits the bacterial cell wall synthesis, thereby exerting its bactericidal properties. Beta-lactams act by interfering with synthesis of the bacterial cell wall.

After administration, Ceftiofur is quickly metabolised to desfuroylceftiofur, the principal active metabolite. Desfuroylceftiofur has an equivalent anti-microbial activity to Ceftiofur against the bacteria involved in respiratory disease in animals. The active metabolite is reversibly bound to plasma proteins. Due to transportation with these proteins, the metabolite concentrates at a site of infection, is active and remains active in the presence of necrotic tissue and debris.


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